5-羟色胺受体2A抗体

产品货号：

BN40347R
中文名称：

5-羟色胺受体2A抗体
英文名称：

Rabbit anti-5HT2A Receptor Polyclonal antibody
品牌：

Biorigin

货号

产品规格

售价

备注
BN40347R-100ul

100ul

¥2360.00

交叉反应：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Sheep) 推荐应用：WB,IHC-F,IF,ELISA
BN40347R-200ul

200ul

¥3490.00

交叉反应：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Sheep) 推荐应用：WB,IHC-F,IF,ELISA

产品描述

英文名称	5HT2A Receptor
中文名称	5-羟色胺受体2A抗体
别名	SR-2A; 5 HT 2; 5 HT 2A; 5 HT2 receptor; 5 HT2A; 5 hydroxytryptamine receptor 2A; 5-HT-2; 5-HT-2A; 5-hydroxytryptamine 2A receptor; 5-hydroxytryptamine receptor 2A; 5HT2A_HUMAN; HTR 2; HTR 2A; HTR2; HTR2A; Serotonin receptor 2A.
研究领域	心血管细胞生物神经生物学细胞膜受体 G蛋白偶联受体新陈代谢 G蛋白信号
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Mouse, Rat, (predicted: Dog, Pig, Cow, Horse, Sheep, )
产品应用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	53kDa
细胞定位	细胞膜
性状	Liquid
浓度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human 5HT2A Receptor:51-150/471 <Extracellular>
亚型	IgG
纯化方法	affinity purified by Protein A
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
产品介绍	This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production. Subunit: Interacts with MPDZ and INADL. May interact with MPP3, PRDX6, DLG4, DLG1, CASK, APBA1 and MAGI2. Subcellular Location: Cell membrane. Localizes to the post-synaptic thickening of axo-dendritic synapses. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P28223 Gene ID: 3356 Database links: Entrez Gene: 3356 Human Entrez Gene: 15558 Mouse Entrez Gene: 29595 Rat Omim: 182135 Human SwissProt: P28223 Human SwissProt: P35363 Mouse SwissProt: P14842 Rat Unigene: 654586 Human Unigene: 72630 Human Unigene: 214351 Mouse Unigene: 10294 Rat Unigene: 146756 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.